搅拌是痴呆症患病率高的神经精神症状之一，可以对日常生活（ADL）的活动产生负面影响，以及个体的独立性。检测搅拌剧集可以帮助提前及时地提供痴呆症（PLWD）的人们。分析搅拌剧集还将有助于识别可修改的因素，例如环境温度和睡眠中的睡眠，导致个体搅动。这项初步研究提出了一种监督学习模型，用于分析PLWD中搅动风险，使用家庭监控数据。家庭监控数据包括来自2019年4月2021年4月至6月至6月20日至6月20日至6月至6月间PLWD的运动传感器，生理测量和厨房电器的使用。我们应用经常性的深度学习模型，以识别验证和记录的临床监测团队验证和记录的搅拌集团。我们提出了评估拟议模型的功效的实验。拟议的模型平均召回79.78％的召回，27.66％的精确度和37.64％的F1分数在采用最佳参数时得分，表明识别搅动事件的良好能力。我们还使用机器学习模型讨论使用连续监测数据分析行为模式，并探索临床适用性以及敏感性和特异性监控应用之间的选择。

The cooperation of a human pilot with an autonomous agent during flight control realizes parallel autonomy. A parallel-autonomous system acts as a guardian that significantly enhances the robustness and safety of flight operations in challenging circumstances. Here, we propose an air-guardian concept that facilitates cooperation between an artificial pilot agent and a parallel end-to-end neural control system. Our vision-based air-guardian system combines a causal continuous-depth neural network model with a cooperation layer to enable parallel autonomy between a pilot agent and a control system based on perceived differences in their attention profile. The attention profiles are obtained by computing the networks' saliency maps (feature importance) through the VisualBackProp algorithm. The guardian agent is trained via reinforcement learning in a fixed-wing aircraft simulated environment. When the attention profile of the pilot and guardian agents align, the pilot makes control decisions. If the attention map of the pilot and the guardian do not align, the air-guardian makes interventions and takes over the control of the aircraft. We show that our attention-based air-guardian system can balance the trade-off between its level of involvement in the flight and the pilot's expertise and attention. We demonstrate the effectivness of our methods in simulated flight scenarios with a fixed-wing aircraft and on a real drone platform.

The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bottlenecks faced by the community in tackling the research questions posed. To shed light on the status quo of algorithm development in the specific field of biomedical imaging analysis, we designed an international survey that was issued to all participants of challenges conducted in conjunction with the IEEE ISBI 2021 and MICCAI 2021 conferences (80 competitions in total). The survey covered participants' expertise and working environments, their chosen strategies, as well as algorithm characteristics. A median of 72% challenge participants took part in the survey. According to our results, knowledge exchange was the primary incentive (70%) for participation, while the reception of prize money played only a minor role (16%). While a median of 80 working hours was spent on method development, a large portion of participants stated that they did not have enough time for method development (32%). 25% perceived the infrastructure to be a bottleneck. Overall, 94% of all solutions were deep learning-based. Of these, 84% were based on standard architectures. 43% of the respondents reported that the data samples (e.g., images) were too large to be processed at once. This was most commonly addressed by patch-based training (69%), downsampling (37%), and solving 3D analysis tasks as a series of 2D tasks. K-fold cross-validation on the training set was performed by only 37% of the participants and only 50% of the participants performed ensembling based on multiple identical models (61%) or heterogeneous models (39%). 48% of the respondents applied postprocessing steps.

With the progress of sensor technology in wearables, the collection and analysis of PPG signals are gaining more interest. Using Machine Learning, the cardiac rhythm corresponding to PPG signals can be used to predict different tasks such as activity recognition, sleep stage detection, or more general health status. However, supervised learning is often limited by the amount of available labeled data, which is typically expensive to obtain. To address this problem, we propose a Self-Supervised Learning (SSL) method with a pretext task of signal reconstruction to learn an informative generalized PPG representation. The performance of the proposed SSL framework is compared with two fully supervised baselines. The results show that in a very limited label data setting (10 samples per class or less), using SSL is beneficial, and a simple classifier trained on SSL-learned representations outperforms fully supervised deep neural networks. However, the results reveal that the SSL-learned representations are too focused on encoding the subjects. Unfortunately, there is high inter-subject variability in the SSL-learned representations, which makes working with this data more challenging when labeled data is scarce. The high inter-subject variability suggests that there is still room for improvements in learning representations. In general, the results suggest that SSL may pave the way for the broader use of machine learning models on PPG data in label-scarce regimes.

The field of cybersecurity is evolving fast. Experts need to be informed about past, current and - in the best case - upcoming threats, because attacks are becoming more advanced, targets bigger and systems more complex. As this cannot be addressed manually, cybersecurity experts need to rely on machine learning techniques. In the texutual domain, pre-trained language models like BERT have shown to be helpful, by providing a good baseline for further fine-tuning. However, due to the domain-knowledge and many technical terms in cybersecurity general language models might miss the gist of textual information, hence doing more harm than good. For this reason, we create a high-quality dataset and present a language model specifically tailored to the cybersecurity domain, which can serve as a basic building block for cybersecurity systems that deal with natural language. The model is compared with other models based on 15 different domain-dependent extrinsic and intrinsic tasks as well as general tasks from the SuperGLUE benchmark. On the one hand, the results of the intrinsic tasks show that our model improves the internal representation space of words compared to the other models. On the other hand, the extrinsic, domain-dependent tasks, consisting of sequence tagging and classification, show that the model is best in specific application scenarios, in contrast to the others. Furthermore, we show that our approach against catastrophic forgetting works, as the model is able to retrieve the previously trained domain-independent knowledge. The used dataset and trained model are made publicly available

Bayesian optimization (BO) is increasingly employed in critical applications such as materials design and drug discovery. An increasingly popular strategy in BO is to forgo the sole reliance on high-fidelity data and instead use an ensemble of information sources which provide inexpensive low-fidelity data. The overall premise of this strategy is to reduce the overall sampling costs by querying inexpensive low-fidelity sources whose data are correlated with high-fidelity samples. Here, we propose a multi-fidelity cost-aware BO framework that dramatically outperforms the state-of-the-art technologies in terms of efficiency, consistency, and robustness. We demonstrate the advantages of our framework on analytic and engineering problems and argue that these benefits stem from our two main contributions: (1) we develop a novel acquisition function for multi-fidelity cost-aware BO that safeguards the convergence against the biases of low-fidelity data, and (2) we tailor a newly developed emulator for multi-fidelity BO which enables us to not only simultaneously learn from an ensemble of multi-fidelity datasets, but also identify the severely biased low-fidelity sources that should be excluded from BO.

The ongoing transition from a linear (produce-use-dispose) to a circular economy poses significant challenges to current state-of-the-art information and communication technologies. In particular, the derivation of integrated, high-level views on material, process, and product streams from (real-time) data produced along value chains is challenging for several reasons. Most importantly, sufficiently rich data is often available yet not shared across company borders because of privacy concerns which make it impossible to build integrated process models that capture the interrelations between input materials, process parameters, and key performance indicators along value chains. In the current contribution, we propose a privacy-preserving, federated multivariate statistical process control (FedMSPC) framework based on Federated Principal Component Analysis (PCA) and Secure Multiparty Computation to foster the incentive for closer collaboration of stakeholders along value chains. We tested our approach on two industrial benchmark data sets - SECOM and ST-AWFD. Our empirical results demonstrate the superior fault detection capability of the proposed approach compared to standard, single-party (multiway) PCA. Furthermore, we showcase the possibility of our framework to provide privacy-preserving fault diagnosis to each data holder in the value chain to underpin the benefits of secure data sharing and federated process modeling.

线性状态空间模型（SSM）的状态过渡矩阵的适当参数化，然后是标准非线性，使他们能够从顺序数据中有效地学习表示形式，从。在本文中，我们表明，当线性液体时恒定（LTC）状态空间模型给出诸如S4之类的结构SSM时，我们可以进一步改善。 LTC神经网络是带有输入依赖性状态过渡模块的因果连续神经网络，这使他们学会在推理时适应传入的输入。我们表明，通过使用对角和S4中引入的状态过渡矩阵的对角线加低级分解以及一些简化的基于LTC的结构状态空间模型（称为Liquid-S4）实现了新的最新最先进的最先进跨序列建模任务具有长期依赖性（例如图像，文本，音频和医疗时间序列）的艺术概括，在远程竞技场基准中的平均性能为87.32％。在完整的原始语音命令识别中，数据集Liquid-S4的精度达到96.78％，与S4相比，参数计数降低了30％。性能的额外增益是液体-S4的核结构的直接结果，该结构考虑了训练和推理过程中输入序列样本的相似性。

与高维数据集的探索性分析（例如主成分分析（PCA））相反，邻居嵌入（NE）技术倾向于更好地保留高维数据的局部结构/拓扑。然而，保留局部结构的能力是以解释性为代价的：诸如T-分布的随机邻居嵌入（T-SNE）或统一的歧管近似和投影（UMAP）等技术没有提供拓扑结构的介绍（UMAP）（UMAP）（UMAP）（UMAP）（UMAP）（UMAP）（UMAP）。在相应的嵌入中看到的群集）结构。在这里，我们提出了基于PCA，Q-残基和Hotelling的T2贡献的化学计量学领域的不同“技巧”，并结合了新型可视化方法，从而得出了邻居嵌入的局部和全局解释。我们展示了我们的方法如何使用标准的单变量或多变量方法来识别数据点组之间的歧视性特征。

多模式信息在医疗任务中经常可用。通过结合来自多个来源的信息，临床医生可以做出更准确的判断。近年来，在临床实践中使用了多种成像技术进行视网膜分析：2D眼底照片，3D光学相干断层扫描（OCT）和3D OCT血管造影等。我们的论文研究了基于深度学习的三种多模式信息融合策略，以求解视网膜视网膜分析任务：早期融合，中间融合和分层融合。常用的早期和中间融合很简单，但不能完全利用模式之间的互补信息。我们开发了一种分层融合方法，该方法着重于将网络多个维度的特征组合在一起，并探索模式之间的相关性。这些方法分别用于使用公共伽马数据集（Felcus Photophs和OCT）以及Plexelite 9000（Carl Zeis Meditec Inc.）的私人数据集，将这些方法应用于青光眼和糖尿病性视网膜病变分类。我们的分层融合方法在病例中表现最好，并为更好的临床诊断铺平了道路。